Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ InSolution™ PKR Inhibitor
The InSolution™ PKR Inhibitor, also referenced under CAS 608512-97-6, controls the biological activity of PKR. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ DNA-PK Inhibitor
The DNA-PK Inhibitor, also referenced under CAS 20357-25-9, controls the biological activity of DNA-PK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Ras/Rac Transformation Blocker, SCH 51344
Ras/Rac Transformation Blocker, SCH 51344, CAS 171927-40-5, is a blocker of Ras-induced malignant transformation and Ras/Rac-dependent dissociation of EMS1 from the actin-myosin II complex.
MilliporeSigma™ Calbiochem™ Anthrax Lethal Factor Protease Inhibitor, In-2-LF
The Anthrax Lethal Factor Protease Inhibitor, In-2-LF controls the biological activity of Anthrax Lethal Factor Protease. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ InSolution™ STAT3 Inhibitor III, WP1066
The InSolution™ STAT3 Inhibitor III, WP1066, also referenced under CAS 857064-38-1, controls the biological activity of STAT3. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Gö 6976
Gö 6976, CAS 136194-77-9, is a cell-permeable, reversible, and ATP-competitive inhibitor of PKC (IC50 = 7.9 nM for rat brain). Exhibits selectively for PKCα (IC50 = 2.3 nM) and βI (IC50 = 6.2 nM).
MilliporeSigma™ Calbiochem™ InSolution™ TLR4 Inhibitor, TAK-242
A 25 mM (2 mg/221 μL) sterile-filtered solution of TLR4 Inhibitor, TAK-242 in DMSO.
MilliporeSigma™ Calbiochem™ Cyclopamine-KAAD
Cyclopamine- KAAD, CAS 306387-90-6, is a cell-permeable potent analog of Cyclopamine (Cat. No. 239803) that specifically inhibits Hedgehog (Hh) signaling with similar or lower toxicity (IC50 = 20 nM).
MilliporeSigma™ Calbiochem™ bpV(bipy)
A potent inhibitor of phosphotyrosine phosphatase (Ki = 100 nM for insulin receptor dephosphorylation).
MilliporeSigma™ Calbiochem™ CBFβ-Runx1 Inhibitor II, Ro5-3335
A cell-permeable benzodiazepine that suppresses CBFα/Runx1-CBFβ transactivation activity (25μM; 293-0 cells) via direct bindings to both subunits of the heterodimeric transcription factor complex
MilliporeSigma™ Calbiochem™ InSolution™ GSK-3 Inhibitor IX
The InSolution™ GSK-3 Inhibitor IX, also referenced under CAS 667463-62-9, controls the biological activity of GSK-3. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ ALDH3A1 Inhibitor, CB29
A cell permeable, selective, reversible, substrate-binding site directed inhibitor of aldehyde dehydrogenase ALDH3A1 (Ki = 4.7 μM, IC50 = 16 μM).
MilliporeSigma™ Calbiochem™ InSolution™ Hh/Gli Antagonist, GANT61
The InSolution™ Hh/Gli Antagonist, GANT61, also referenced under CAS 500579-04-4, controls the biological activity of Hh/Gli. This small molecule/inhibitor is primarily used for Cell Signaling applications.
MilliporeSigma™ Calbiochem™ MMP-1/MMP-9 Substrate, Fluorogenic
An excellent quenched fluorescence substrate for MMP-1 and MMP-9.
MilliporeSigma™ Calbiochem™ Sphingosine Kinase 1 Inhibitor II, PF-543
The Sphingosine Kinase 1 Inhibitor II, PF-543 controls the biological activity of Sphingosine Kinase 1. This small molecule/inhibitor is primarily used for Cell Structure applications.